Dermal delivery of HSP47 siRNA with NOX4-modulating mesoporous silica-based nanoparticles for treating fibrosis
作者： Jingga Morry , Worapol Ngamcherdtrakul , Shenda Gu , Shaun M. Goodyear , David J. Castro
DOI: 10.1016/J.BIOMATERIALS.2015.07.005
关键词:
摘要: … Thus, we hypothesize that MSNP can remove ROS from the vicinity of the fibrotic tissue and alleviate fibrogenesis by reducing NOX4-associated fibroblast activation and proliferation. …
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