Campylobacter jejuni-associated hemolytic-uremic syndrome in a mother and daughter

摘要: A mother and daughter with Campylobacter jejuni-associated hemolytic-uremic syndrome (HUS) are discussed. The was hospitalized bloody diarrhea HUS; C jejuni isolated from her stool. 2-year-old had been admitted five days prior to HUS following a three-day prodrome of vomiting diarrhea. Multiple stool cultures were negative for enteric pathogens; however, not obtained until the eighth hospital day after antibiotic therapy. Extensive investigation failed identify another cause diarrheal illness or in our patients. Indirect immunofluorescent antibody titers 1:32 1:16 daughter, respectively. An asymptomatic 9-month-old son his an titer 1:64. Three other family members asymptomatic, stool-culture negative, less than equal 1:4. susceptibility develop antigenic stimulus is illustrated by patients presented. need systematic all cases potential markers, as well exhaustive etiologic search, emphasized.