PARP-1 inhibitor sensitizes arsenic trioxide in hepatocellular carcinoma cells via abrogation of G2/M checkpoint and suppression of DNA damage repair
作者： Qingying Luo , Yang Li , Jianjun Deng , Zunzhen Zhang
DOI: 10.1016/J.CBI.2014.12.007
关键词:
摘要: Arsenic trioxide (ATO) is successfully used to treat hematological malignancies. However, the clinical application of the agent in solid tumors is largely limited by its dose-dependent …
elsevier.com
sci-hub.se 参考文章(49)
Neus Martínez-Bosch, Mar Iglesias, Jessica Munné-Collado, Carlos Martínez-Cáceres, Mireia Moreno, Carmen Guerra, Jose Yélamos, Pilar Navarro, Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer. The Journal of Pathology. ,vol. 234, pp. 214- 227 ,(2014) , 10.1002/PATH.4384
Yang Wang, Yudan Wei, Haiying Zhang, Yanfen Shi, Yulin Li, Ronggui Li, Arsenic trioxide induces apoptosis of p53 null osteosarcoma MG63 cells through the inhibition of catalase Medical Oncology. ,vol. 29, pp. 1328- 1334 ,(2012) , 10.1007/S12032-011-9848-5
Giovanna Damia, Silvio Garattini, The pharmacological point of view of resistance to therapy in tumors. Cancer Treatment Reviews. ,vol. 40, pp. 909- 916 ,(2014) , 10.1016/J.CTRV.2014.05.008
Julie K. Horton, Donna F. Stefanick, Jana M. Naron, Padmini S. Kedar, Samuel H. Wilson, Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure Journal of Biological Chemistry. ,vol. 280, pp. 15773- 15785 ,(2005) , 10.1074/JBC.M413841200
Liu Yang, Kun Huang, Xiangrao Li, Meng Du, Xiang Kang, Xi Luo, Lu Gao, Cheng Wang, Yanqing Zhang, Chun Zhang, Qiangsong Tong, Kai Huang, Fengxiao Zhang, Dan Huang, Identification of Poly(ADP-Ribose) Polymerase-1 as a Cell Cycle Regulator through Modulating Sp1 Mediated Transcription in Human Hepatoma Cells PLoS ONE. ,vol. 8, pp. e82872- ,(2013) , 10.1371/JOURNAL.PONE.0082872
Michael J. Carrozza, Donna F. Stefanick, Julie K. Horton, Padmini S. Kedar, Samuel H. Wilson, PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM. DNA Repair. ,vol. 8, pp. 1264- 1272 ,(2009) , 10.1016/J.DNAREP.2009.07.010
Santiago Diaz-Moralli, Míriam Tarrado-Castellarnau, Anibal Miranda, Marta Cascante, Targeting cell cycle regulation in cancer therapy. Pharmacology & Therapeutics. ,vol. 138, pp. 255- 271 ,(2013) , 10.1016/J.PHARMTHERA.2013.01.011
Béla Csete, Zsuzsanna Lengyel, Zsolt Kádár, Zita Battyáni, Poly(adenosine diphosphate-ribose) polymerase-1 expression in cutaneous malignant melanomas as a new molecular marker of aggressive tumor. Pathology & Oncology Research. ,vol. 15, pp. 47- 53 ,(2009) , 10.1007/S12253-008-9086-0
QING XIA, YUCHEN CAI, ROUJUN PENG, GUOSHENG WU, YANXIA SHI, WENQI JIANG, The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition. International Journal of Oncology. ,vol. 44, pp. 735- 744 ,(2014) , 10.3892/IJO.2013.2240
Pankaj Chaudhary, Rajendra Sharma, Mukesh Sahu, Jamboor K. Vishwanatha, Sanjay Awasthi, Yogesh C. Awasthi, 4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway Journal of Biological Chemistry. ,vol. 288, pp. 20532- 20546 ,(2013) , 10.1074/JBC.M113.467662