Recombination at ColE1 cer requires the Escherichia coli xerC gene product, a member of the lambda integrase family of site-specific recombinases

摘要: Site-specific recombination at the plasmid ColE1 cer site requires Escherichia coli chromosomal gene xerC. The xerC has been localized to 85-min region of E. chromosome, between cya and uvrD. nucleotide sequences flanking regions have determined. encodes a protein with calculated molecular mass 33.8 kDa. This substantial sequence similarity lambda integrase family site-specific recombinases is probably recombinase. expressed as part multicistronic unit that includes dapF two other open reading frames.