Pulmonary Function in HIV-Infected Recreational Drug Users in the Era of Anti- Retroviral Therapy

摘要: Background: Individuals with HIV infection commonly have pulmonary function abnormalities, including airflow obstruction and diffusion impairment, which may be more prevalent among recreational drug users. To date, the relationship between use abnormalities those remains unclear. Objective: determine associations obstruction, radiographic emphysema in men women HIV. Methods: Cross-sectional analysis of self-reported data from a cohort 121 63 Primary outcomes were presence (yes/no) of: 1) (pre- or post-bronchodilator forced expiratory volume 1 second/forced vital capacity 1% lung voxels <-950 Hounsfield units). Exposures interest frequency use, recent (since last study visit) any lifetime use. We used logistic regression to primary outcomes. Results: HIV-infected reported at 56.0% 31.0% their visits, respectively, 48.8% 39.7% since visit. Drug was not associated airway women. Recent crack cocaine independently moderate impairment (odds ratio 17.6; 95% confidence interval 1.3-249.6, p=0.03). Conclusions: In this cross-sectional analysis, we found that common HIVinfected Given increasing prevalence infection, severity chronic diseases could significant impact on disease management.