N,N,N-Trimethyl Chitosan and Its Potential Bactericidal Activity: CurrentAspects and Technological Applications

作者: Débora Facchi , Suelen Facchi , Alessandro Martins

DOI: 10.4172/2332-0877.1000291

关键词:

摘要: N,N,N-Trimethyl chitosan (TMC) is one of most important derivative with stronger bactericidal property. Currently, the TMC has been attracted considerable attention, because it contains quaternized ammonium moieties (-+N(CH3)3) in its network. Its cationic property leads to a renowned power. Besides, appropriate biocompatibility, biodegradability, mucoadhesive capacity and greater solubility at pH close physiological condition regarding chitosan. In this way, there are not sources revision papers toward action. So, work reports potential be applied many fields, depicting performance, as well as, mechanism some current technological aspects that must considered.

参考文章(23)
Alessandro F. Martins, Heveline D.M. Follmann, Johny P. Monteiro, Elton G. Bonafé, Samara Nocchi, Cleiser T.P. Silva, Celso V. Nakamura, Emerson M. Girotto, Adley F. Rubira, Edvani C. Muniz, Polyelectrolyte complex containing silver nanoparticles with antitumor property on Caco-2 colon cancer cells International Journal of Biological Macromolecules. ,vol. 79, pp. 748- 755 ,(2015) , 10.1016/J.IJBIOMAC.2015.05.036
Heveline DM Follmann, Alessandro F Martins, Thatyane M Nobre, Joana D Bresolin, Thelma SP Cellet, Patrícia Valderrama, Daniel S Correa, Edvani C Muniz, Osvaldo N Oliveira Jr, None, Extent of shielding by counterions determines the bactericidal activity of N,N,N-trimethyl chitosan salts Carbohydrate Polymers. ,vol. 137, pp. 418- 425 ,(2016) , 10.1016/J.CARBPOL.2015.10.083
Alessandro F. Martins, Suelen P. Facchi, Heveline D.M. Follmann, Adriana P. Gerola, Adley F. Rubira, Edvani C. Muniz, Shielding effect of ‘surface ion pairs’ on physicochemical and bactericidal properties of N,N,N-trimethyl chitosan salts Carbohydrate Research. ,vol. 402, pp. 252- 260 ,(2015) , 10.1016/J.CARRES.2014.10.002
Tao Xu, Meihua Xin, Mingchun Li, Huili Huang, Shengquan Zhou, Synthesis, characteristic and antibacterial activity of N,N,N-trimethyl chitosan and its carboxymethyl derivatives Carbohydrate Polymers. ,vol. 81, pp. 931- 936 ,(2010) , 10.1016/J.CARBPOL.2010.04.008
Alessandro F. Martins, Johny P. Monteiro, Elton G. Bonafé, Adriana P. Gerola, Cleiser T.P. Silva, Emerson M. Girotto, Adley F. Rubira, Edvani C. Muniz, Bactericidal activity of hydrogel beads based on N,N,N-trimethyl chitosan/alginate complexes loaded with silver nanoparticles Chinese Chemical Letters. ,vol. 26, pp. 1129- 1132 ,(2015) , 10.1016/J.CCLET.2015.04.032
Milena Ignatova, Nevena Manolova, Iliya Rashkov, Novel antibacterial fibers of quaternized chitosan and poly(vinyl pyrrolidone) prepared by electrospinning European Polymer Journal. ,vol. 43, pp. 1112- 1122 ,(2007) , 10.1016/J.EURPOLYMJ.2007.01.012
Honglue Tan, Rui Ma, Chucheng Lin, Ziwei Liu, Tingting Tang, Quaternized chitosan as an antimicrobial agent: antimicrobial activity, mechanism of action and biomedical applications in orthopedics. International Journal of Molecular Sciences. ,vol. 14, pp. 1854- 1869 ,(2013) , 10.3390/IJMS14011854
Rachid Belalia, Stéphane Grelier, Mohammed Benaissa, Véronique Coma, New bioactive biomaterials based on quaternized chitosan. Journal of Agricultural and Food Chemistry. ,vol. 56, pp. 1582- 1588 ,(2008) , 10.1021/JF071717+
Lihong Fan, Jing Yang, Huan Wu, Zhihai Hu, Jiayan Yi, Jun Tong, Xiaoming Zhu, Preparation and characterization of quaternary ammonium chitosan hydrogel with significant antibacterial activity. International Journal of Biological Macromolecules. ,vol. 79, pp. 830- 836 ,(2015) , 10.1016/J.IJBIOMAC.2015.04.013