Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate.
作者： Nezih Oktar , Tayfun Dalbasti
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摘要: Congenital protein S deficiency is associated with an increased risk of venous thrombosis. A14-year-old boy presented epileptic seizures and thrombosis the superior sagittal sinus frontal hemorrhagic infarction after ingestion 50 mg dimenhydrinate, antiemetic drug. The patient was found to be heterozygous for factor V Leiden mutation had a functional deficiency. He recovered completely within month conservative treatment. Dimenhydrinate may have disrupted subclinical pre-existing condition in this case.
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