Conformational changes in human lens proteins in cataract

作者: John J. Harding

DOI: 10.1042/BJ1290097

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摘要: The reactivity of protein thiol groups in human lens and the susceptibility proteins to tryptic digestion were investigated. Both found be greater some cataractous lenses, indicating that have unfolded during cataractogenesis. Almost all tyrosine normal reacts with tetranitromethane is therefore probably on outside major proteins.

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