Sex steroids are necessary in the second postnatal week for the expression of male alloparental behavior in prairie voles (Microtus ochragaster).

摘要: Sex steroids play a significant role in organizing male social behavior, which is associated with low levels of pro-social behavior and high aggression. However, the highly males unclear. The authors tested hypothesis that sex facilitate expression prairie voles (Microtus ochragaster), predicting inhibition testosterone estradiol would reduce spontaneous-alloparental behavior. Treatment aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD) or androgen receptor blocker flutamide, days 8-14, significantly reduced alloparental 21-day old males. While both treatments increased pup-directed aggression, there were differential treatment effects. Flutamide altered initial response, increasing latency to enter pup cage likelihood retreat from contact. ATD-treated showed increases sniffing latencies lick huddle. Results indicate endogenous development effects estrogens androgens differ.