A study on Aflatoxins Analysis in The Herb Medicines

作者: Sung-Deuk Lee , Yeon-Sun Kim , Nam-Hoon Kim , Hwa-Soon Kim , Ki-Young Han

DOI:

关键词:

摘要: The increase in the consumption of herb medicines have made their use a public health problem due to potential fungal contamination and risk presence mycotoxins. 360 samples were evaluated for aflatoxin contamination. natural occurrence aflatoxins these determined using immunoaffinity column clean up high performance liquid chromatography (HPLC) with post-column derivatization. For analyzed, mean levels (incidence) AFB1, AFB2, AFG1 AFG2 positive 1.4 µg/kg (46.4%), 0.4 (25.4%), 1.1 (37.8%) 0.9 (24.3%), respectively. Recoveries full analytical procedure 71.7~99.7% 88.1~99.2% 82.8~95.5% 77.9~90.0% AFG2. excess cancer estimated potency B1 (7 (mg/kg/day) �1 HBsAgand 230 HBsAg + ) 1.30 × 10 �5 ~ 1.22 �7 hepatits B surface antigen negative (HBsAg � 3.31 �4 ~3 .12× �6 In conclusion, although used study low, further actions are also required undertake program herbal surveys order access mycotoxin overall so that safety will be protected.

参考文章(25)
Richard J. Cole, Richard H. Cox, Handbook of toxic fungal metabolites Handbook of toxic fungal metabolites.. ,(1981)
Pushkar N Kaul, Balawant S Joshi, E Domingo, A Mas, E Yuste, N Pariente, S Sierra, M Gutiérrez-Rivas, L Menéndez-Arias, Doreen Ma, Chaman Lal Kaul, Poduri Ramarao, Jay A Glasel, Pushkar N Kaul, Balawant S Joshi, Alternative medicine: herbal drugs and their critical appraisal--part II. Progress in drug research. ,vol. 56, pp. 1- 75 ,(2001) , 10.1007/978-3-0348-8308-5_1
Mimi C. Yu, Chi-Chun Mo, Fu-Sun Yeh, Si Luo, Brian E. Henderson, Myron J. Tong, Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, China. Cancer Research. ,vol. 49, pp. 2506- 2509 ,(1989)
John D. Groopman, David L. Eaton, The toxicology of aflatoxins: human health, veterinary and agricultural significance. Academic Press.. ,(1993)
Vinod Kumar, M.S. Basu, T.P. Rajendran, Mycotoxin research and mycoflora in some commercially important agricultural commodities Crop Protection. ,vol. 27, pp. 891- 905 ,(2008) , 10.1016/J.CROPRO.2007.12.011
Antonio Flavio Midio, Renata Rodrigues Campos, Myrna Sabino, Occurrence of aflatoxins B1, B2, G1 and G2 in cooked food components of whole meals marketed in fast food outlets of the city of Sa~o Paulo, SP, Brazil Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment. ,vol. 18, pp. 445- 448 ,(2001) , 10.1080/02652030120070
Sofie Monbaliu, Aibo Wu, Dabing Zhang, Carlos Van Peteghem, Sarah De Saeger, Multimycotoxin UPLC-MS/MS for tea, herbal infusions and the derived drinkable products. Journal of Agricultural and Food Chemistry. ,vol. 58, pp. 12664- 12671 ,(2010) , 10.1021/JF1033043