Acupoint injection therapy for diabetic retinopathy: A protocol for systematic review and meta-analysis.

摘要: Background Diabetic retinopathy (DR) is a common diabetic microvascular complication, and it also the main cause of blindness in adults. At present, some studies have reported acupoint injection for treatment DR. However, effectiveness safety are still uncertain. This study aims to evaluate efficacy patients with Methods The databases English (PubMed, Embase, Cochrane Library, Web Science) Chinese (China National Knowledge Infrastructure, Scientific Journal Database, Wanfang Biomedical Literatures Database) will be retrieved. Published randomized controlled trials quasi-randomized on topic retrieved by 2 investigators independently. We apply fixed-effect model or random effect basis heterogeneity test employ RevMan 5.3 software data synthesis. total effective rate selected as primary outcome, visual acuity, hemorrhage areas, exudates, capillary nonperfusion hemorheological indicators, mean defect field, glycated hemoglobin, adverse events secondary outcomes. Results comprehensively summarize high-quality determine Conclusion systematic review this currently published evidence DR further guide its promotion application. Protocol registration number INPLASY2020110026.