P53 activating peptides

作者: Farid John Ghadessy , Walter Goh

DOI:

关键词:

摘要: The present invention is directed to p53 activating peptides. further describes methods for generating these peptides and the use of

参考文章(15)
Tina Jakobsen, Liselotte Brix, Jorgen Scholler, Henrik Pedersen, Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics ,(2008)
Sophia J. Tsai, Udayaditya Sen, Lei Zhao, William B. Greenleaf, Jhimli Dasgupta, Edoardo Fiorillo, Valeria Orrú, Nunzio Bottini, Xiaojiang S. Chen, Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation . Biochemistry. ,vol. 48, pp. 4838- 4845 ,(2009) , 10.1021/BI900166Y
Howard M. Grey, Brian D. Livingston, Maria A. Vitiello, Ralph T. Kubo, Robert W. Chesnut, Alessandro Sette, Scott Southwood, Esteban Celis, John Sidney, Inducing cellular immune responses to hepatitis b virus using peptide and nucleic acid compositions ,(2000)
N. Issaeva, A. Friedler, P. Bozko, K. G. Wiman, A. R. Fersht, G. Selivanova, Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 13303- 13307 ,(2003) , 10.1073/PNAS.1835733100
Christopher J. Brown, Chit F. Cheok, Chandra S. Verma, David P. Lane, Reactivation of p53: from peptides to small molecules. Trends in Pharmacological Sciences. ,vol. 32, pp. 53- 62 ,(2011) , 10.1016/J.TIPS.2010.11.004
G Selivanova, K G Wiman, Reactivation of mutant p53: molecular mechanisms and therapeutic potential. Oncogene. ,vol. 26, pp. 2243- 2254 ,(2007) , 10.1038/SJ.ONC.1210295
M. Yonezawa, DNA display for in vitro selection of diverse peptide libraries Nucleic Acids Research. ,vol. 31, ,(2003) , 10.1093/NAR/GNG119
I. M. Ota, A. Varshavsky, A gene encoding a putative tyrosine phosphatase suppresses lethality of an N-end rule-dependent mutant. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 2355- 2359 ,(1992) , 10.1073/PNAS.89.6.2355
Y Tang, Chenghua Liu, Vinod Asundi, Chongjun Xu, Ping Zhou, Yunqing Ma, Jian-Rui Wang, Qing Zhao, Feiyan Ren, Rui-Hong Chen, Dunrui Wang, Zhiwei Wang, Tom Wehrman, Jie Zhang, Xiaohong Qian, Radoje Drmanac, Novel nucleic acids and polypeptides ,(2002)