Metal-free synthesis of cyclic di-oxoguanidines via one-pot sequential transformation of amines, carbodiimides and acyl dichlorides
作者： Fei Zhao , Yang Wang , Wen-Xiong Zhang , Zhenfeng Xi
DOI: 10.1039/C2OB25799H
关键词:
摘要: The one-pot sequential reaction of various amines, carbodiimides, and acyl dichlorides has been achieved for the first time under metal-free conditions to provide symmetric cyclic di-oxoguanidines via an unexpected 2,2-dichloro-imidazolidindione intermediate. Acyl have a dual function: serve as third component activate carbodiimides. In sharp contrast, AlMe3-catalyzed from same substrates gives isomer.
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