Lewis Acid Catalyzed Conjugate Addition and the Formation of Heterocycles using Michael Acceptors under Solvent‐Free Conditions
作者： Alemayehu Mekonnen , Rolf Carlson
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摘要: Conjugate addition and conjugate-addition-initiated ring closure (CAIRC) reactions of β-dicarbonyl compounds with Michael acceptors have been studied using several Lewis acid catalysts under solvent-free conditions. Excellent chemoselectivity was obtained when various were treated compounds. On the other hand, 2-bromo-2-cyclopentenone 3-bromo-3-vinyl methyl ketone furnished 2,3-dihydrofurans instead 1,4-adducts same reagents.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
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