Determination of organochlorine pesticides in complex matrices by single-drop microextraction coupled to gas chromatography-mass spectrometry.

摘要: Abstract A rapid and simple single-drop microextraction method (SDME) has been used to preconcentrate eighteen organochlorine pesticides (OCPs) from water samples with a complex matrix. Exposing two microlitre toluene drop an aqueous sample contaminated OCPs proved excellent preconcentration prior analysis by gas chromatography–mass spectrometry (GC–MS). Plackett-Burman design was for screening central composite optimizing the significant variables in order evaluate several possibly influential and/or interacting factors. The studied were volume, agitation speed, ionic strength extraction time. optimum experimental conditions of proposed SDME were: 2 μL microdrop exposed 37 min 10 mL containing 0% w/v NaCl stirred at 380 rpm. calculated calibration curves gave high-level linearity all target analytes correlation coefficients ranging between 0.9991 0.9999. repeatability method, expressed as relative standard deviation, varied 5.9 9.9% ( n  = 8). detection limits range 0.022–0.101 μg L −1 using GC–MS selective ion monitoring. LOD values obtained are able detect these matrices required EPA Method 625. Analysis spiked effluent wastewater revealed that matrix had no effect on eleven but exerted notable other analytes.