Epidemiology of Gestational Trophoblastic Diseases

摘要: The gestational trophoblastic diseases have, until recently, attracted relatively little attention from epidemiologists. many descriptive studies that have been conducted over the last four decades helped to define geographic distribution of these and provided evidence for a large number potential risk factors. In general studies, while serving generate new interesting hypotheses, not designed adequately evaluate significance disease associations, or consider question interrelationships between various testing hypotheses requires different approach, such as traditional casecontrol design, which compares data obtained women included in case series those carefully selected control group, it is only few years full-scale case-control on undertaken. A major stimulus renewed activity has come recent insights into biology genetics hydatidiform moles, served better pathological entities complete partial moles. Knowledge cellular mechanisms involved naturally led questions concerning possible environmental familial (genetic) factors may be associated with, predispose to, observed events.