Pregnancy after limb-sparing hemipelvectomy for Ewing's sarcoma. A case report and review of the literature.

作者: Izumi Goto Chihara , Hisao Osada , Yoshinori Iitsuka , Kentaro Masuda , Souei Sekiya

DOI: 10.1159/000074823

关键词:

摘要: Ewing's sarcoma of the bone is a malignant tumor occurring mostly in adolescence and was considered to have poor prognosis. With recent advances multi-agent combined chemotherapy, prognosis has improved, more patients with primary lesions pelvis opt for limb-saving surgeries. In present case, left diagnosed at age 11 patient underwent chemotherapy limb-sparing hemipelvectomy. She became pregnant 22. After an uneventful pregnancy, she delivered healthy child 37 weeks gestation by cesarean section because pelvic distortion. This first reported case pregnancy delivery after hemipelvectomy due sarcoma. Since multi-modality treatment improves survival, number women who desire expected increase future. valuable that will provide useful information such patients.

参考文章(11)
Michael Paulussen, Birgit Fr??hlich, Herbert J??rgens, Ewing tumour: incidence, prognosis and treatment options. Pediatric Drugs. ,vol. 3, pp. 899- 913 ,(2001) , 10.2165/00128072-200103120-00003
Claude Turc-Carel, Alain Aurias, Francine Mugneret, Sarab Lizard, Isabelle Sidaner, Christian Volk, Jean Paul Thiery, Sylviane Olschwang, Irene Philip, Marie Pierre Berger, Thierry Philip, Gilbert M. Lenoir, André Mazabraud, Chromosomes in Ewing's sarcoma. I. An evaluation of 85 cases and remarkable consistency of t(11;22)(q24;q12) Cancer Genetics and Cytogenetics. ,vol. 32, pp. 229- 238 ,(1988) , 10.1016/0165-4608(88)90285-3
P.A. Bergh, J. Bonamo, J.L. Breen, Pregnancy after hemipelvectomy: a case report and review of the literature International Journal of Gynecology & Obstetrics. ,vol. 27, pp. 277- 283 ,(1988) , 10.1016/0020-7292(88)90020-3
Diane Snyder, Ronald Thomas, Pregnancy complicated by hemipelvectomy: case presentations and review of the literature. American Journal of Perinatology. ,vol. 6, pp. 363- 366 ,(1989) , 10.1055/S-2007-999616
H. Stacy Nicholson, John J. Mulvihill, Julianne Byrne, Late effects of therapy in adult survivors of osteosarcoma and Ewing's sarcoma. Medical and Pediatric Oncology. ,vol. 20, pp. 6- 12 ,(1992) , 10.1002/MPO.2950200103
D. M. Parkin, C. A. Stiller, J. Nectoux, International variations in the incidence of childhood bone tumours. International Journal of Cancer. ,vol. 53, pp. 371- 376 ,(1993) , 10.1002/IJC.2910530305
Biljana Novakovic, Thomas R. Fears, Marc E. Horowitz, Margaret A. Tucker, Leonard H. Wexler, Late Effects of Therapy in Survivors of Ewing's Sarcoma Family Tumors Journal of Pediatric Hematology Oncology. ,vol. 19, pp. 220- 225 ,(1997) , 10.1097/00043426-199705000-00008
Lee Jh, Nuss Rc, Pregnancy following hemipelvectomy. Report of a case. Obstetrics & Gynecology. ,vol. 29, pp. 789- ,(1967)
Stavrakas Pa, Sanders Gt, Sling support during pregnancy after hemipelvectomy: case report. Archives of Physical Medicine and Rehabilitation. ,vol. 64, pp. 331- ,(1983)
Alan W. Yasko, Mark E. Johnson, Surgical management of primary bone sarcomas. Hematology-oncology Clinics of North America. ,vol. 9, pp. 719- 732 ,(1995) , 10.1016/S0889-8588(18)30067-4