Pilot in vivo investigation of cerium oxide nanoparticles as a novel anti-obesity pharmaceutical formulation

作者: Mario Giorgi , Gianni Ciofani , Antonella Rocca , Stefania Moscato , Francesca Ronca

DOI: 10.1016/J.NANO.2015.05.001

关键词:

摘要: … Since overweight correlates with an increased oxidative stress, our aim is to investigate the antioxidant effects of cerium oxide nanoparticles (nanoceria) as a potential pharmaceutical …

参考文章(58)
Ui-Hyun Park, Ji-Cheon Jeong, Jae-Sik Jang, Mi-Ran Sung, HyeSook Youn, Sook-Jeong Lee, Eun-Joo Kim, Soo-Jong Um, Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells. Biological & Pharmaceutical Bulletin. ,vol. 35, pp. 1525- 1533 ,(2012) , 10.1248/BPB.B12-00254
V Muzakova, J Skalicky, R Kandar, M Meloun, T Rousar, Oxidative stress and metabolic syndrome in obese adults with and without controlled diet restriction. Bratislavské lekárske listy. ,vol. 110, pp. 152- 157 ,(2009)
Courtney A Cohen, Elizabeth Terrell Strawn, Beverly A Rzigalinski, Cerium oxide nanoparticles increase lifespan and protect against free radical-mediated toxicity The FASEB Journal. ,vol. 20, ,(2006)
Jun Hong Park, Sean Bong Lee, An essential role for Ewing sarcoma gene (EWS) in early white adipogenesis Obesity. ,vol. 23, pp. 138- 144 ,(2015) , 10.1002/OBY.20934
Karla M. Pires, Olesya Ilkun, Marina Valente, Sihem Boudina, Treatment with a SOD mimetic reduces visceral adiposity, adipocyte death, and adipose tissue inflammation in high fat‐fed mice Obesity. ,vol. 22, pp. 178- 187 ,(2014) , 10.1002/OBY.20465
E. A. Wang, D. I. Israel, S. Kelly, D. P. Luxenberg, Bone Morphogenetic Protein-2 Causes Commitment and Differentiation in C3Hl0T1/2 and 3T3 Cells Growth Factors Journal. ,vol. 9, pp. 57- 71 ,(1993) , 10.3109/08977199308991582
Milena De Nicola, Lina Ghibelli, Fanny Caputo, Pharmacological potential of bioactive engineered nanomaterials. Biochemical Pharmacology. ,vol. 92, pp. 112- 130 ,(2014) , 10.1016/J.BCP.2014.08.015
Karin L. Heckman, William DeCoteau, Ana Estevez, Kenneth J. Reed, Wendi Costanzo, David Sanford, James C. Leiter, Jennifer Clauss, Kylie Knapp, Carlos Gomez, Patrick Mullen, Elle Rathbun, Kelly Prime, Jessica Marini, Jamie Patchefsky, Arthur S. Patchefsky, Richard K. Hailstone, Joseph S. Erlichman, Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain. ACS Nano. ,vol. 7, pp. 10582- 10596 ,(2013) , 10.1021/NN403743B