Effects of anesthesia on the respiratory system.

作者: Göran Hedenstierna , Lennart Edmark

DOI: 10.1016/J.BPA.2015.08.008

关键词:

摘要: Most anesthetics cause a loss of muscle tone that is accompanied by fall in the resting lung volume. The lowered volume promotes cyclic (tidal) or continuous airway closure. High inspired oxygen fractions rapid absorption gas behind closed airways, resulting atelectasis. This chapter deals with these mechanisms more detail, and it addresses possible measures to keep open use recruitment maneuvers, and/or end-expiratory positive pressure, as well interaction different concentrations. effects on ventilation/perfusion matching pulmonary exchange are also discussed.

参考文章(69)
E. Maripuu, U. Ebmeyer, T. Hachenberg, Christof M. Strang, Göran Hedenstierna, Improved ventilation-perfusion matching by abdominal insufflation (pneumoperitoneum) with CO2 but not with air. Minerva Anestesiologica. ,vol. 79, pp. 617- 625 ,(2013)
L. EDMARK, U. AUNER, M. ENLUND, E. ÖSTBERG, G. HEDENSTIERNA, Oxygen concentration and characteristics of progressive atelectasis formation during anaesthesia. Acta Anaesthesiologica Scandinavica. ,vol. 55, pp. 75- 81 ,(2011) , 10.1111/J.1399-6576.2010.02334.X
C. GRIVANS, S. LUNDIN, O. STENQVIST, S. LINDGREN, Positive end-expiratory pressure-induced changes in end-expiratory lung volume measured by spirometry and electric impedance tomography. Acta Anaesthesiologica Scandinavica. ,vol. 55, pp. 1068- 1077 ,(2011) , 10.1111/J.1399-6576.2011.02511.X
G. Nakos, H. Tsangaris, S. Liokatis, E. Kitsiouli, M. E. Lekka, Ventilator-associated pneumonia and atelectasis: evaluation through bronchoalveolar lavage fluid analysis. Intensive Care Medicine. ,vol. 29, pp. 555- 563 ,(2003) , 10.1007/S00134-003-1680-8
Göran Hedenstierna, Hans Ulrich Rothen, Respiratory Function During Anesthesia: Effects on Gas Exchange Comprehensive Physiology. ,vol. 2, pp. 69- 96 ,(2012) , 10.1002/CPHY.C080111
P R Westbrook, S E Stubbs, A D Sessler, K Rehder, R E Hyatt, Effects of anesthesia and muscle paralysis on respiratory mechanics in normal man. Journal of Applied Physiology. ,vol. 34, pp. 81- 86 ,(1973) , 10.1152/JAPPL.1973.34.1.81
A. M. Boriek, J. R. Rodarte, Inferences on passive diaphragm mechanics from gross anatomy Journal of Applied Physiology. ,vol. 77, pp. 2065- 2070 ,(1994) , 10.1152/JAPPL.1994.77.5.2065
J. L. Benumof, Mechanism of decreased blood flow to atelectatic lung Journal of Applied Physiology. ,vol. 46, pp. 1047- 1048 ,(1979) , 10.1152/JAPPL.1979.46.6.1047
H.U Rothen, B Sporre, G Engberg, G Wegenius, A Reber, G Hedenstierna, Prevention of atelectasis during general anaesthesia The Lancet. ,vol. 345, pp. 1387- 1391 ,(1995) , 10.1016/S0140-6736(95)92595-3