作者: Shridhar Hegde , Jeffery Carter
DOI: 10.1016/S0065-7743(04)39025-1
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摘要: Publisher Summary This chapter discusses 27 drugs which were manufactured in the year 2003 related to cardiovascular, anticancer, allergic and respiratory diseases, male erectile dysfunction, attention deficit/hyperactivity disorder. The cardiovascular sector had four new entering market 2003: Crestor™ (rosuvastatin), Livalo ® (pitavastatin), Calblock (azelnidipine), a gradual-onset, long-acting calcium antagonist, Inspra™(eplerenone). anticancer field saw introduction of three drugs: Velcade (bortezomib), Erbitux (cetuximab), Bexxar (tositumomab). In two entities reached market: Rupafin (rupatidine fumarate) Xolair (omalizumab). area endocrine metabolic appeared on Somavert (pegvisomant) Aldurazyme (laronidase). Zavesca™ (miglustat), glucosylceramide synthase inhibitor, was introduced as first orally active treatment for type 1 Gaucher's disease. Following success Viagra (sildenafil) dysfunction (ED), phosphodiesterase 5 (PDE5) inhibitors launched: Cialis™ (tadalafil) Levitra™ (vardenafil). CNS represented by launch Strattera™ (atomoxetine). Two biologic immunosuppressive agents also Amevive (alefacept) Raptiva™ (efalizumab). A significant NBE last Humira™ (adalimumab). other notable launched FluMist™ (influenza virus live).