Acute toxicity and responses of antioxidant systems to dibutyl phthalate in neonate and adult Daphnia magna.

作者: Chenchen Shen , Jie Wei , Tianyi Wang , Yuan Wang

DOI: 10.7717/PEERJ.6584

关键词:

摘要: Dibutyl phthalate (DBP) poses a severe threat to aquatic ecosystems, introducing hazards both species and human health. The ecotoxic effects of DBP on organisms have not been fully investigated. This study investigates acute toxicity, oxidative damage, antioxidant enzyme parameters in neonate adult Daphnia magna exposed DBP. obtained results show comparable toxic responses neonates adults. median lethal concentrations (LC50) for 24 48 h were 3.48 2.83 mg/L, respectively. LC50 adults the same exposure durations 4.92 4.31 Increased hydrogen peroxide malondialdehyde found at h, while total capacity decreased. Superoxide dismutase activity increased significantly 0.5 mg/L DBP, subsequently diminished higher prolonged exposure. Catalase glutathione S-transferases activities decreased markedly changes observed be time concentration dependent. Overall, these data indicated that more pronounced than adults, injury may main mechanism toxicity. These provide functional link lipid peroxidation, capacity, levels response

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