Mechanism of elimination reactions
作者： T. Yoshida , Y. Yano , S. Oae
DOI: 10.1016/S0040-4020(01)91699-0
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摘要: Abstract The rates of the base-catalysed elimination a series substituted α-phenylethyl bromides have been determined in t-BuOK-t-BuOH, t-BuOK-t-BuOH-DMSO and EtONa-EtOH systems. Hammett ϱ values obtained were, although small not linear correlation with σ values, positive all cases. β-Methyl group retarded rate t-BuOK-t-BuOH t-BuOK-t-BuOH-DMSO, but enhanced it EtONa-EtOH. β-Hydrogen kinetic isotope effects were 5·0, 3·5 3·4, respectively. nature transition states is discussed light these observations.
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