Atrial Electromechanical Interval May Predict Cardioembolic Stroke in Apparently Low Risk Elderly Patients with Paroxysmal Atrial Fibrillation

摘要: Background A considerable number of patients with atrial fibrillation (AF) develop cardioembolic stroke (CE) despite low CHADS2 score. We examined the possibility that use electromechanical interval (AEMI) improves prediction CE in paroxysmal AF (PAF), particularly those score. Methods We consecutively enrolled 108 nonvalvular PAF and 52 healthy subjects as controls. The were divided into 2 groups depending on presence (n = 36) or absence (n = 72) history CE. Left (LA) volume index (LAVI), peak myocardial velocity during late diastole (a'), AEMI time from onset P-wave to lateral a' measured. Results Patients had significantly larger LAVI, longer AEMI, lower than Area under curves for a', identifying 0.70, 0.69, 0.88, respectively. Multivariate logistic regression analysis indicated age, antiarrhythmic drugs, but not LAVI independently associated PAF. categorized risk by score (i.e. score = 0 1, n = 60), prolonged (>82 msec) higher rates ≤82 msec (48% vs. 15%, P < 0.05). Conclusion As compared echocardiographic parameters LA size function, appears be more useful patients. may enable detect high patients, especially