Sex chromosome marker: clinical significance and DNA characterization.
作者： Virginia P. Johnson , Paul G. McDonough , Sau W. Cheung , Li Sun
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摘要: Two patients are described with a virtually identical marker sex chromosome that was so small as to defy classification by conventional cytogenetic studies. DNA hybridization Y probes allows into or non-Y, and in situ X centromere specific sequences, non-X. One patient proven have fragment, the second, an fragment. characterization is important since prognosis clinical management depends on proper identification of chromosome.
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