Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.
作者： Dhanalakshmi Chinnasamy , Leslie J. Fairbairn , James Neuenfeldt , Jonathan S. Treisman , John P. Hanson
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摘要: Lentiviral vectors are capable of efficiently transducing nondividing and slowly dividing cells, including hematopoietic stem resulting in stable integration sustained transgene expressi...
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