Lens Culinaris Agglutinin-Reactive Fraction of Alpha-Fetoprotein as a Marker of Prognosis and a Monitor of Recurrence of Hepatocellular Carcinoma After Curative Liver Resection

摘要: The aim of this study was to determine the role Lens culinaris agglutinin-reactive fraction alpha-fetoprotein (AFP-L3) as a prognostic marker and monitor recurrence after curative resection hepatocellular carcinoma (HCC). From December 2002 May 2004, 395 consecutive patients with HCC who underwent partial hepatectomy were included in study. tumor characteristics clinical outcomes positive preoperative postoperative AFP-L3 compared those negative results. A high ratio total AFP an indicator pathologic aggressiveness. Patients had significantly earlier (median time 22.0 ± 2.4 months vs 45.0 ± 6.9 months, P < .001) when Significantly more continuously or negative-turn-positive results surgery developed recurrence, particularly distant metastases, overall disease-free survivals shorter than group. Positive predicted aggressive behavior, higher poorer outcomes. increased proportion should be aggressively treated closely followed-up.