Carcinogenicity, mutagenicity and teratogenicity of nickel

摘要: Abstract Nickel is widely used in the metallurgical industry, and, although not released extensively into environment, may represent a hazard to human health. Owing their low absorption from gastrointestinal tract, nickel compounds, except carbonyl, are essentially non-toxic after ingestion. Epidemiological investigations and experimental studies have demonstrated that certain compounds extremely potent carcinogens inhalation, but also carcinogenic risk limited conditions of occupational exposure. The relatively small number mutagenicity performed up now do yet allow definite conclusions as whether mutagenic. can cross placenta has embryotoxic teratogenic properties. principal man, beside its carcinogenicity, however, ability provoke reactions sensitization.