Three-dimensional suspension printing of dosage forms

作者: Charles W Rowe , Jill K Sherwood , Lewis Wendy E Pryce , James A Fairweather , Chen-Chao Wang

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摘要: The invention includes dispensing a suspension containing solid particles for use in manufacturing dosage form or other biomedical article by 3DP. contains suspended liquid. may be one more Active Pharmaceutical Ingredients. of material that are insoluble the liquid, they substance have already dissolved liquid up to saturation level and present concentration beyond what can dissolved. In addition particles, also contain substances it, either Ingredients (API) without API. One aspect prevention agglomeration adding several categories additives suspending Another manipulating surface charge an API prevent from agglomerating. A further amorphous has greater bioavailability than corresponding crystalline material. Yet another system providing continuous circulation such remain dispersed suspension.

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