Additively manufactured porous metallic biomaterials

摘要: Additively manufactured (AM, =3D printed) porous metallic biomaterials with topologically ordered unit cells have created a lot of excitement and are currently receiving attention given their great potential for improving bone tissue regeneration preventing implant-associated infections. This paper presents an overview the various aspects design, manufacturing, bio-functionalization these materials from "designer material" viewpoint discusses how rational design principles could be used to underlying lattice structures in such way that desired properties including mechanical properties, fatigue behavior, mass transport (e.g., permeability, diffusivity), surface area, geometrical features affecting rate curvature) simultaneously optimized. We discuss different types topological those based on beam-based cells, sheet-based triply periodic minimal surfaces), functional gradients. also highlight use topology optimization algorithms AM biomaterials. The topology-property relationships all above-mentioned presented as well followed by discussion applicable techniques pros cons base (i.e., bioinert biodegradable metals). Finally, we huge (internal) surfaces pore space respectively accommodation drug delivery vehicles so enhance performance minimize risk conclude general suggesting some possible areas future research.