作者: Ronald E. White
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摘要: The science of drug metabolism, like any other science, has advanced from simple beginnings (by today's standards) to its present state. One can examine the path that been taken understand forces driving direction evolution this science. trends discovered then be used make reasonable extrapolations about changes might expected in future. That exercise is subject article. main focus will on metabolism as practiced industrial environment, representing author's experience well principal arena practical applications discussion draw mainly broad phenomena occurring application discovery and development.