Biosynthesis of tetrapyrroles

摘要: The biosynthesis of 5-aminolaevulinic acid and its transformation into uroporphyrinogen III (P.M. Jordan). Early isotopic studies on the origin tetrapyrrole ring. from glycine. glutamate. porphobilinogen. III. Mechanism stereochemistry enzymes involved in conversion haem (M. Akhtar). Uroporphyrinogen decarboxylase [uroporphyrinogen carboxylase]. Coproporphyrinogen oxidase. Protoporphyrinogen IX Ferrochelatase. vitamin B12 (A.I. Scott P.J. Santander). carbon balance. Stereochemistry methyl group insertion corrinoid biosynthesis. Concerning fate protons. Uro'gen is a precursor B12. Characterization intermediacy isobacteriochlorins P.shermanii. methylation sequence: pulse experiments. Timing decarboxylation step. protein balance Factors S1-S4, isomeric, tetramethylated corphinoids derived uro'gen I. transferases. Biosynthesis neucleotide loop coenzyme Evolutionary aspects Biochemistry F430, nickel porphinoid methanogenesis (H.C. Friedman, A. Klein R.K. Thauer). Structural relations to other tetrapyrroles. glutamate via dihydrosirohydrochlorin. Properties free F430 including redox behaviour. Function as prosthetic M reductase methanogenesis. Comparative analysis genes encoding reductase. regulation photosynthetic pigment formation plants algae (S.I. Beale J.D. Weinstein). variety functions plant algal biosynthetic route. Regulation. structure bacteriochlorophylls (K.M. Smith). Nomenclature. Occurrence structures. Biosynthesis. Jordan I.A. Mgbeje). Genes cobalamin (B12) bacteriochlorophyll chlorophyll