作者: Thomas J. Wang , Ramachandran S. Vasan
DOI: 10.1161/CIRCULATIONAHA.104.490599
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摘要: Hypertension is a powerful risk factor for fatal and nonfatal cardiovascular disease events. Data from observational studies indicate that this continuous, without evidence of threshold, down to blood pressures as low 115/75 mm Hg.1 Randomized controlled trials have convincingly shown treatment hypertension reduces the stroke, coronary heart disease, congestive failure, mortality.2,3 Because currently affects 1 in 4 American adults (≈65 million people 1999 2000)4 may affect >90% individuals during their lifetimes,5 adequate control pressure enormous public health importance. However, recent many two thirds those with United States are either untreated or undertreated.6 Studies based on national data community cohorts shed light reasons underlying poor control, but several questions remain unanswered. In article, we review contemporary epidemiology uncontrolled by (1) defining what constitutes “controlled hypertension”; (2) describing current magnitude problem, including temporal trends; (3) summarizing consequences hypertension; (4) examining clinical correlates appraising patient- physician-related factors related pressure; (5) identifying future research directions, potential interventions address problem. “uncontrolled hypertension” signifies inadequately treated rather than resistant treatment, might be observed secondary causes such renal artery stenosis. The definition high has changed over time differs between guidelines proposed expert bodies. Variation influences number classified having hypertension7 contribute …