The association of bullous pemphigoid and malignant disease: a case control study.

摘要: In a case control study, the incidence of malignant disease in 84 patients with bullous pemphigoid (BP) was compared 168 controls. The rate (past, concurrent or during follow-up) BP 17.9% to 5.3% A number malignancies occurring group may be doubtful significance, being either temporally very remote partially attributable treatment. and malignancy (within 8 weeks) 6.0% suggesting that there is probably slight excess BP, but insufficient warrant extensive investigation pursuit cancer. Comparison without cancer identified no clinical immunopathological subgroups whom investigations would indicated. Three both were HLA-DR 13 positive, which point an immunogenetic predisposition diseases.