Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection

摘要: The specific role of the perirhinal (PRC), entorhinal (ERC) and parahippocampal cortices (PHC) in supporting familiarity-based recognition remains unknown. An fMRI study explored whether these medial temporal lobe (MTL) structures responded same way or differentially to familiarity as a function stimulus type at recognition. A secondary aim was explore hippocampus responds equally strong recollection this is influenced by kind involved. Univariate multivariate analyses revealed that responses PRC, ERC, PHC amygdala are material-specific. Specifically, PRC ERC selectively object familiarity, while both scene familiarity. only memory for faces. did not respond any three types stimuli, but it all stimuli. This true even when contrasted accurate Overall, findings suggest MTL neocortices depends on memory, whereas independent cuing stimulus. © 2016 Authors Hippocampus Published Wiley Periodicals, Inc.