A review of the behavioral and neurochemical consequences of early weaning in rodents

摘要: Abstract In mammals, mother–infant bonding is based on the dependence of infant mother for sustenance, i . e ., suckles milk, but also involving a need physical contact. Weaning one most important events that occur in developing animals and timing natural weaning dependent environmental resources during nursing period, if mothers rear their offspring under severe conditions, there trade-off between at an earlier time, reducing survival, increased maternal survival. production laboratory rodents are routinely weaned than nature. Disruption can induce behavioral problems, including neuroendocrine stress responses, augmentation fear aggression, reduced behaviour. Here, we review long-lasting effects early adult rodent behavior neuroendocrinology.