A comparison between Mohs micrographic surgery and wide surgical excision for the treatment of dermatofibrosarcoma protuberans.

摘要: Background : There is growing evidence that Mohs micrographic surgery (MMS) the treatment of choice for dermatofibrosarcoma protuberans (DFSP). Objective This study retrospectively compared recurrence rates DFSP after MMS with those wide surgical excision ; results at Mayo Clinic and in world literature were evaluated. In addition, preoperative tumor sizes postoperative defect to determine whether conserved more normal tissue than excision. Methods The medical records 84 patients who had been treated reviewed. They categorized into two groups Results Fifteen underwent follow-up data available one these local (recurrence rate, 6.6% average duration follow-up, 40 months). Thirty-nine four recurrences pulmonary metastases 10% 36 A review revealed neither nor 11 studies which was MMS. Overall, including out results, rate 0.6% (range, 0% 6.6%) total 1.6% (1 64). Including series, 15 18% 60%) 20% (100 489). eight published studies, surgically resected undefined or conservative excisional margins 43% 26% 44% (140 317). margin 2.5 cm deep fascia required complete clearance all tumors Twenty-two percent removed a 0.5 margin, 50% 1.0 67% 1.5 89% 2.0 margin. Conclusion On basis compiled from literature, may be because its high cure maximal conservation tissue. (J Am Acad Dermatol 1996 ;35 :82-7.)