Markers of insulin resistance in day and shift workers aged 30-59 years

摘要: Abstract Objectives. To examine relationships between shift work and markers (metabolic abnormalities) of insulin resistance (IR). Methods. A cross-sectional study 2,824 day 826 workers. All the subjects were male blue-collar workers aged 30–59 years. Four IR [(1) hypertension (systolic blood pressure ≥140 mmHg or diastolic ≥90 mmHg under treatment for hypertension); (2) hyperglycemia (fasting serum glucose ≥7.00 mmol/l diabetes); (3) hypertriglyceridemia triglyceride ≥1.70 mmol/l hyperlipidemia); (4) hypo-HDL-cholesterolemia HDL-cholesterol <1.04 mmol/l)] checked. Subsequently, syndrome, a cluster markers, was expediently diagnosed by number (N) found in each worker. N≥1, N≥2 N≥3 used as cutpoint diagnosis. The prevalence marker syndrome compared two worker groups. Age, body mass index (kg/m2), job, drinking, smoking, exercise confounding factors. Job, schedule lifestyles based on self-administered questionnaires. Results. Hypertriglyceridemia (28.7% workers, 31.2% workers) most prevalent (4.6%), (5.4%) least, four both Approximately half had at least one groups (N≥1; 46.0% 46.6%, respectively). However, full rare (N=4; 0.2% 0.1%, Prevalence any cutpoints increased with age but 50 years older lower than younger In years, all (except hypo-HDL-cholesterolemia) more Contrariwise, older, found. These results not influenced statistical adjustments factors multiple logistic regression analysis. Conclusions. Shift may be associated relations underestimated mainly broad definition healthy-worker effects.