Current and future intratumoral targeted treatment for pancreatic cancer

作者: Paul Zarogoulidis , Paschalis Pavlioglou , Patrick Le Pivert , Nikolaos Machairiotis , Nikolaos Katsikogiannis

DOI: 10.4155/TDE.14.44

关键词:

摘要: Pancreatic cancer is an insidious type of with its symptoms manifested upon extensive disease. The overall 5-year survival rates between 0.4 and 4%. Surgical resection option for only 10% the patients pancreatic cancer. Local recurrence hepatic metastases occur within 2 years after surgery. There are currently several molecular pathways investigated novel targeted treatments on market. However; nature ability to spread locally in primary site lymph nodes indicates that further experimentation local interventional therapies could be a future treatment proposal as palliative care or adjunct gene therapy chemotherapy/radiotherapy. In current review, we will summarize present options

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