Protracted survival after resection of metastatic uveal melanoma.

摘要: BACKGROUND The objective of this study was to evaluate the usefulness resection metastatic uveal melanoma and analyze characteristics patients who may benefit from surgical intervention. PATIENTS AND METHODS Twelve underwent removal metastasis between 1976 1998. Data regarding primary melanoma, systemic metastasis, procedures, outcomes were reviewed retrospectively. RESULTS There seven with liver metastases, two lung one brain metastases in other organs. Median time 8 years. Seven 12 asymptomatic when they found have metastasis. Ten complete No significant complications experienced. recurrence free overall survival periods after 19 months (range, 6–78 months) greater than 27 11–86 months), respectively. Recurrence 5-year rates those 15.6% 53.3%, Three these had no further recurrence. All whose within 5 years developed 2 surgery. In contrast, years, 4 either or second more surgery. CONCLUSIONS Complete provided unexpectedly long without morbidity for selected patients. These results are encouraging justify a trial which eligible randomized standard treatment Cancer 2000;89:1561–8. © 2000 American Society.