Kathon CG: A review
作者： Anton C. de Groot , J. Willem Weyland
DOI: 10.1016/S0190-9622(88)70051-1
关键词:
摘要: Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be frequent cause of contact dermatitis in Europe. In the United States, where CG was introduced some 5 years later, use this system for toiletries is rapidly increasing. Undoubtedly cases sensitization will soon emerge country. Most allergy are caused by moisturizing creams on (slightly) damaged skin. Sensitization cosmetic products previously healthy skin, especially face, does occur but less frequent. Rinse-off do not seem have substantial potential induction elicitation allergic reactions because dilution product allergen with water well short time This review provides synopsis current knowledge emphasis risk diagnostic procedures.
jaad.org
eblue.org 参考文章(23)
Ping Kwong Chan, Robert C. Baldwin, Richard D. Parsons, Jack N. Moss, Robert Stiratelli, Jerry M. Smith, A. Wallace Hayes, Kathon Biocide: Manifestation of Delayed Contact Dermatitis in Guinea Pigs Is Dependent on the Concentration for Induction and Challenge Journal of Investigative Dermatology. ,vol. 81, pp. 409- 411 ,(1983) , 10.1111/1523-1747.EP12522544
James E. Weaver, Caroline Cardin, Howard I. Maibach, Dose‐response assessments of Kathon® biocide (I). Diagnostic use and diagnostic threshold patch testing with sensitized humans Contact Dermatitis. ,vol. 12, pp. 141- 145 ,(1985) , 10.1111/J.1600-0536.1985.TB01083.X
A.C.DE GROOT, J.D. BOS, Preservatives in the European standard series for epicutaneous testing British Journal of Dermatology. ,vol. 116, pp. 289- 292 ,(1987) , 10.1111/J.1365-2133.1987.TB05841.X
Howard I. Maibach, Diagnostic patch test concentration for Kathon CG. Contact Dermatitis. ,vol. 13, pp. 242- 245 ,(1985) , 10.1111/J.1600-0536.1985.TB02557.X
Matti Hannuksela, Heikki Salo, The repeated open application test (ROAT). Contact Dermatitis. ,vol. 14, pp. 221- 227 ,(1986) , 10.1111/J.1600-0536.1986.TB01229.X
N. Hjorth, J. Roed-Petersen, Patch test sensitivity to Kathon® CG Contact Dermatitis. ,vol. 14, pp. 155- 157 ,(1986) , 10.1111/J.1600-0536.1986.TB01195.X
A. Tosti, P. Manuzzi, M. P. de Padova, Contact dermatitis to Kathon CG Contact Dermatitis. ,vol. 14, pp. 326- 327 ,(1986) , 10.1111/J.1600-0536.1986.TB05298.X
C. E. H. Grattan, R. R. M. Harman, R. S. H. Tan, Milk recorder dermatitis. Contact Dermatitis. ,vol. 14, pp. 217- 220 ,(1986) , 10.1111/J.1600-0536.1986.TB01228.X
Anton C. de Groot, Jan D. Bos, Berend A. Jagtman, Derk P. Bruynzeel, Theodoor van Joost, J. Willem Weyland, Contact allergy to preservatives - II Contact Dermatitis. ,vol. 15, pp. 218- 222 ,(1986) , 10.1111/J.1600-0536.1986.TB01340.X
Christine Wright, Elliot Gingold, Stanley Venitt, Christopher Crofton-Sleigh, Mutagenic activity of Kathon, an industrial biocide and cosmetics preservative containing 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one. Mutation Research Letters. ,vol. 119, pp. 35- 43 ,(1983) , 10.1016/0165-7992(83)90035-0