Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET.
作者： Heike E. Daldrup-Link , Christiane Franzius , Thomas M. Link , Daniela Laukamp , Joachim Sciuk
DOI: 10.2214/AJR.177.1.1770229
关键词:
摘要: OBJECTIVE. The purpose of this study was to compare the diagnostic accuracy whole-body MR imaging, skeletal scintigraphy, and 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for detection bone metastases in children.SUBJECTS AND METHODS. Thirty-nine children young adults who were 2-19 years old had Ewing's sarcoma, osteosarcoma, lymphoma, rhabdomyosarcoma, melanoma, Langerhans' cell histiocytosis underwent spin-echo FDG PET initial staging marrow metastases. number location lesions diagnosed with each imaging modality correlated biopsy clinical follow-up as standard reference.RESULTS. Twenty-one patients exhibited 51 Sensitivities 90% PET, 82% 71% scintigraphy; these data significantly different (p < 0.05). False-negative wer...
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