Mapping genomic regions associated with growth rate in pigs.

作者: E Casas-Carrillo , A Prill-Adams , S G Price , A C Clutter , B W Kirkpatrick

DOI: 10.2527/1997.7582047X

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摘要: The objective of this study was to identify genomic regions associated with postweaning average daily gain (ADG) in swine. Two families were produced using sires obtained from the cross lines divergently selected for high and low growth rate. Sires mated 29 unrelated dams that 124 115 offspring. Average recorded every individual; mean ADG .593 ± .007 kg/d .619 .009 two families. Selective genotyping performed as a prescreening procedure potentially ADG. A total 75 genetic markers used between both Markers identified nominally significant ( P < .05) an individual marker analysis subsequently typed all individuals. still after complete family then reevaluated together flanking interval mapping analysis. single region on chromo- some 3, flanked by Sw2429 Sw251, second had logarithm odds score 2.9, which is suggestive linkage quantitative trait locus Differences .033 individuals inheriting alternative paternal alleles most marker.

参考文章(24)
R. W. Doerge, G. A. Churchill, Permutation Tests for Multiple Loci Affecting a Quantitative Character Genetics. ,vol. 142, pp. 285- 294 ,(1996) , 10.1093/GENETICS/142.1.285
Leslie S. Sargeant, Ron Okimoto, James E. Womack, Michel Georges, Ina Hoeschele, Margaret Mackinnon, Michael R. Steele, Anuradha Mishra, Alan T. Pasquino, Dablia Nielsen, Anita Sorensen, Xuyun Zhao, Mapping Quantitative Trait Loci Controlling Milk Production in Dairy Cattle by Exploiting Progeny Testing Genetics. ,vol. 139, pp. 907- 920 ,(1995) , 10.1093/GENETICS/139.2.907
John W. Keele, Gary A. Rohrer, Craig W. Beattie, Leeson J. Alexander, Tim P. Smith, A microsatellite linkage map of the porcine genome. Genetics. ,vol. 136, pp. 231- 245 ,(1994) , 10.1093/GENETICS/136.1.231
H. Geldermann, Investigations on inheritance of quantitative characters in animals by gene markers I. Methods. Theoretical and Applied Genetics. ,vol. 46, pp. 319- 330 ,(1975) , 10.1007/BF00281673
William M. Strauss, Preparation of Genomic DNA from Mammalian Tissue Current protocols in molecular biology. ,vol. 42, ,(1998) , 10.1002/0471142727.MB0202S42
Eric Lander, Leonid Kruglyak, Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results Nature Genetics. ,vol. 11, pp. 241- 247 ,(1995) , 10.1038/NG1195-241
Xiangfeng Cui, Joe Gerwin, William Navidi, Honghua Li, Michael Kuehn, Norman Arnheim, Gene-centromere linkage mapping by PCR analysis of individual oocytes. Genomics. ,vol. 13, pp. 713- 717 ,(1992) , 10.1016/0888-7543(92)90146-J
G.G.M. Habets, R.A. van der Kammen, V. Willemsen, M. Balemans, J. Wiegant, J.G. Collard, Sublocalization of an invasion-inducing locus and other genes on human chromosome 7. Cytogenetic and Genome Research. ,vol. 60, pp. 200- 205 ,(1992) , 10.1159/000133336
Jun Takeda, Anthony A. Fernald, Kazuya Yamagata, Michelle M. Le Beau, Graeme I. Bell, Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization Genomics. ,vol. 26, pp. 638- 639 ,(1995) , 10.1016/0888-7543(95)80195-R