The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts
作者： J. G. Tew , D. Qin , J. Wu , G. F. Burton , A. K. Szakal
DOI: 10.1007/978-3-662-13141-1_2
关键词:
摘要: This review focuses on how follicular dendritic cells (FDC) and associated antigens are involved in germinal center reactions changes FDC function alter humoral immune responses. In normal animals, trap antigen the form of complexes these presented to B cells, which then process present obtained from T providing help needed for development, production memory high affinity antibody. We will involvement handling describe steps some detail. addition, we aware a number dependent that abnormal aged retrovirus infected mice men. These abnormalities be discussed context what is happening young adult animals where recall antibody responses normal.
springer.com
sci-hub.st 参考文章(71)
Inghirami G, Thorbecke Gj, Tsiagbe Vk, The physiology of germinal centers. Critical Reviews in Immunology. ,vol. 16, pp. 381- 421 ,(1996)
G S Wood, The immunohistology of lymph nodes in HIV infection: a review Progress in AIDS pathology. ,vol. 2, pp. 25- 32 ,(1990)
K Tenner-Racz, P Racz, C Thome, CG Meyer, PJ Anderson, SF Schlossman, NL Letvin, None, Cytotoxic effector cell granules recognized by the monoclonal antibody TIA-1 are present in CD8+ lymphocytes in lymph nodes of human immunodeficiency virus-1-infected patients. American Journal of Pathology. ,vol. 142, pp. 1750- 1758 ,(1993)
R Rupper, A K Szakal, B A Fuchs, J G Tew, G F Burton, B S Bhogal, A Masuda, Follicular dendritic cell function and murine AIDS. Immunology. ,vol. 81, pp. 41- 46 ,(1994)
Takashi Makinodan, Marguerite M.B. Kay, Age influence on the immune system. Advances in Immunology. ,vol. 29, pp. 287- 330 ,(1980) , 10.1016/S0065-2776(08)60047-4
F Danon, P Aucouturier, J L Preud'homme, D Gouet, J Gombert, L J Couderc, A G Saimot, J P Clauvel, S Matheron, Serum immunoglobulin G subclass dysbalances in the lymphadenopathy syndrome and acquired immune deficiency syndrome. Clinical and Experimental Immunology. ,vol. 63, pp. 234- ,(1986)
R M Dilosa, A K Szakal, J G Tew, K Maeda, A Masuda, Germinal center B cells and antibody production in the bone marrow Journal of Immunology. ,vol. 146, pp. 4071- 4077 ,(1991)
A K Szakal, J G Tew, L D Shultz, G F Burton, Z F Kapasi, Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells. Journal of Immunology. ,vol. 150, pp. 2648- 2658 ,(1993)
A K Szakal, J G Tew, M H Kosco, A novel in vivo follicular dendritic cell-dependent iccosome-mediated mechanism for delivery of antigen to antigen-processing cells. Journal of Immunology. ,vol. 140, pp. 341- 353 ,(1988)
A K Szakal, K L Holmes, J G Tew, Transport of immune complexes from the subcapsular sinus to lymph node follicles on the surface of nonphagocytic cells, including cells with dendritic morphology. Journal of Immunology. ,vol. 131, pp. 1714- 1727 ,(1983)