A model for assessing interference.

摘要: Most studies of analytical interference indicate the magnitude but not type interference. We developed a model for that assesses following types interference: independent analyte concentration, dependent on and combination two. The experimental design is an orthogonally arranged matrix with progressively increasing concentrations interfering agent. Multiple regression these variables (concentration analyte, concentration agent, product two) used to determine magnitude, direction, significance each Applying study by hemoglobin determinations creatinine, direct bilirubin, total bilirubin showed interferes determination creatinine