The effect of sodium hypochlorite on potential pathogenic traits of Candida albicans and other Candida species

摘要: Strains of Candida albicans, krusei, kefyr, tropicalis, parapsilosis and guilliermondii were grown in the presence or absence concentrations sodium hypochlorite below minimal inhibitory concentration tested for a range characteristics that may be associated with pathogenicity. Sodium is used routinely hospitals Australia disinfection procedures, these experiments designed to assess efficacy as sterilizing agent acrylic dentures. showed varying abilities adhere surfaces present oral cavity. reduced adhesion all C. albicans strains most other species both polystyrene buccal epithelial cells. A biofilm Streptococcus gordonii polystyrene. However, able coaggregate S. suspension, one strain GDH 2346, showing greater coaggregating ability than species. increased coaggregation Examination cell wall proteins from growth amount protein some existing bands and, number detectable ranging 56 26 kDa. Only 4 produce hyphae, 3 same proteinase. Hypochlorite rate blastospore hyphal transition but had no effect on proteinase production activity. It concluded at function an anti-adhesin not affect their more pathogenic characteristics.