Mass-based encoding and qualitative analysis of combinatorial libraries
作者： Craig Daniel Wagner , Hendrik Mario Geysen , Daniel Stuart Kinder
DOI:
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摘要: The insertion of isotopically labeled portions into solid state combinatorial synthesis constructs followed by mass spectrometer, mass-based nuclear magnetic resonance spectrometry or infrared analysis allows for the physical, non-chemical encoding large numbers products.
google.com.tr 参考文章(14)
Viktor Krchnak, Michal Lebl, Kit S. Lam, Petr Kocis, Selectively cleavabe linners based on iminodiacetic acid esters for solid phase peptide synthesis ,(1994)
Lawrence W. Dillard, Michael H. Wigler, Michael H. J. Ohlmeyer, John C. Reader, W. Clark Still, Supports and combinatorial chemical libraries thereof encoded by non-sequencable tags ,(1995)
W. Clark Still, Lawrence W. Dillard, Michael H. Wigler, Michael H. J. Ohlmeyer, John C. Reader, Methods for recording the reaction history of a solid support ,(1995)
Michael C. Needels, William J. Dower, Mark A. Gallop, Ronald W. Barrett, Tagged synthetic oligomer libraries ,(1992)
H. Mario Geysen, Craig D. Wagner, Wanda M. Bodnar, Christopher J. Markworth, Gillian J. Parke, Frank J. Schoenen, David S. Wagner, Daniel S. Kinder, Isotope or mass encoding of combinatorial libraries Chemistry & Biology. ,vol. 3, pp. 679- 688 ,(1996) , 10.1016/S1074-5521(96)90136-2
Edwin Southern, William Jonathan Thorntree Drive Cummins, Tag reagent and assay method ,(1994)
Dimitris K Agrafiotis, Roger F Bone, Francis R Salemme, Richard M Soll, None, System and method of automatically generating chemical compounds with desired properties ,(1995)
Eric Gordon, Christopher Holmes, William Fitch, Derek MacLean, Zhi-Jie Ni, Nikhil Shah, Mark A. Gallop, Methods for hard-tagging an encoded synthetic library ,(1995)
Haim Kedar, Michael C. Needels, Jeffrey H. Sugarman, Ronald W. Barrett, Richard P. Rava, William J. Dower, Mark A. Gallop, Synthesizing and screening molecular diversity ,(1994)
W. Clark Still, Lawrence W. Dillard, Michael H. Wigler, Michael H. J. Ohlmeyer, John C. Reader, Complex combinatorial chemical libraries encoded with tags ,(1993)