摘要: Many drugs taken by pregnant and nursing women might affect the baby (see Hutchings, 1989). Drug teratogenicity was not a major concern until thalidomide tragedy in early 1960’s. The tranquilizer, produced Germany (by Chemie Grunenthal) improperly tested, widely prescribed Europe to combat “morning sickness” pregnancy. birth of hundreds infants with phocomelia, poorly developed limbs (the “seal flipper” deformity), result. drug sold even face mounting reports malformation, hitherto one rarest. Only when US Food Administration did clear for market banned Europe.