Evaluation of the susceptibility of dermatophytes to antifungal drugs: a new technique.

作者: P. Butty , J.-C. Lebecq , M. Mallié , J.-M. Bastide

DOI: 10.1080/02681219580000771

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摘要: The evaluation of the minimal inhibitory concentration (MIC) for pathogenic fungi is still a technically difficult assay. Insufficient standardization technique often basis problems which appear. Culture characteristics dermatophytes do not favour techniques usually used in bacteriology (Steers agar dilution method). A study was undertaken to compare Steers method and new culture evaluate antifungal compounds on several species dermatophytes. involves drug solid medium Petri dish. Standardized cylinders are cut from plates filled with inocula same size dermatophyte cultures. Such facilitate analysis fungus its natural growth conditions vitro without being submitted disruptive preparative technique. MIC values were similar two methods spite important differences between ...

参考文章(16)
Van Nueten Jm, Niemegeers Cj, Marsboom R, Van Cutsem J, Thienpont D, Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic. Drug Research. ,vol. 25, pp. 224- ,(1975)
Marcel Borgers, Ultrastructural Correlates of Antimycotic Treatment Current topics in medical mycology. ,vol. 2, pp. 1- 39 ,(1988) , 10.1007/978-1-4612-3730-3_1
M. F. Simpanya, The sensitivity of dermatophytes to griseofulvin. Tropical and geographical medicine. ,vol. 42, pp. 100- 102 ,(1990)
T C Granade, W M Artis, Antimycotic susceptibility testing of dermatophytes in microcultures with a standardized fragmented mycelial inoculum. Antimicrobial Agents and Chemotherapy. ,vol. 17, pp. 725- 729 ,(1980) , 10.1128/AAC.17.4.725
Kurt A. Oster, Milton J. Golden, Studies on Alcohol-Soluble Fungistatic and Fungicidal Compounds. I. Evaluation of Fungistatic Laboratory Test Methods *† Journal of the American Pharmaceutical Association. ,vol. 36, pp. 283- 288 ,(1947) , 10.1002/JPS.3030360911
Bodil Pock-Steen, Takasi Kobayasi, Ultrastructure of the Hyphal Wall and Septum of Trichophyton Mentagrophytes Journal of Investigative Dermatology. ,vol. 55, pp. 404- 409 ,(1970) , 10.1111/1523-1747.EP12260512
HENRY FIELD SMYTH, ACTION OF PINE OIL ON SOME FUNGI OF THE SKIN, IN VITRO Archives of Dermatology. ,vol. 26, pp. 1079- 1085 ,(1932) , 10.1001/ARCHDERM.1932.01450031081015
Aletta Georgii, H. C. Korting, Antifungal susceptibility testing with dermatophytes Mycoses. ,vol. 34, pp. 193- 199 ,(2009) , 10.1111/J.1439-0507.1991.TB00643.X
G. Badillet, F. Traore, Dermatophytes et sérologie HIV positive Bulletin de la Société française de mycologie médicale. ,vol. 16, pp. 95- 98 ,(1987)