Drug-induced nephropathies.

摘要: Drug-induced renal disease is a common problem. Drugs cause several syndromes, such as prerenal azotemia, fluid and electrolyte abnormalities, acute tubular necrosis, interstitial nephritis, chronic nephritis. Acute failure due to necrosis the most syndrome frequently caused by aminoglycoside antibiotics, radiographic contrast agents, amphotericin B. Avoidance of these drugs in volume-depleted or hypotensive patients with preexisting those receiving multiple nephrotoxic effective way reduce nephrotoxicity. nephritis an immune process that commonly penicillins, diuretics, allopurinol, nonsteroidal anti-inflammatory drugs, cimetidine, sulfonamides. Prompt recognition cessation responsible drug are usually only necessary therapy. Chronic often seen after prolonged use different types analgesic including aspirin, acetaminophen, drugs. These develop recurrent papillary eventually failure. They also at risk developing transitional cell carcinomas urinary collecting system. Some who cyclosporine fibrosis.