Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways.
作者： Jisheng Ran , Chiyuan Ma , Kai Xu , Langhai Xu , Yuzhe He
DOI: 10.2147/DDDT.S162014
关键词:
摘要: … Our study demonstrated that Schisandrin B ameliorated chondrocytes inflammation and OA via suppression of nuclear factor-κB (NF-κB) and MAPK signal pathways, indicating a …
paperity.org参考文章(26)
Peter, S. Burrage, Matrix Metalloproteinases: Role In Arthritis Frontiers in Bioscience. ,vol. 11, pp. 529- 543 ,(2006) , 10.2741/1817
Elena Losina, Alexander M. Weinstein, William M. Reichmann, Sara A. Burbine, Daniel H. Solomon, Meghan E. Daigle, Benjamin N. Rome, Stephanie P. Chen, David J. Hunter, Lisa G. Suter, Joanne M. Jordan, Jeffrey N. Katz, Lifetime Risk and Age at Diagnosis of Symptomatic Knee Osteoarthritis in the US Arthritis Care & Research. ,vol. 65, pp. 703- 711 ,(2013) , 10.1002/ACR.21898
Dick Heinegård, Tore Saxne, The role of the cartilage matrix in osteoarthritis Nature Reviews Rheumatology. ,vol. 7, pp. 50- 56 ,(2011) , 10.1038/NRRHEUM.2010.198
Ke-Wu Zeng, Tai Zhang, Hong Fu, Geng-Xin Liu, Xue-Mei Wang, Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide-induced microglia European Journal of Pharmacology. ,vol. 692, pp. 29- 37 ,(2012) , 10.1016/J.EJPHAR.2012.05.030
Louise Murphy, Todd A. Schwartz, Charles G. Helmick, Jordan B. Renner, Gail Tudor, Gary Koch, Anca Dragomir, William D. Kalsbeek, Gheorghe Luta, Joanne M. Jordan, Lifetime risk of symptomatic knee osteoarthritis Arthritis & Rheumatism. ,vol. 59, pp. 1207- 1213 ,(2008) , 10.1002/ART.24021
Massimo Sabatini, Christophe Lesur, Marie Thomas, Agnès Chomel, Philippe Anract, Guillaume de Nanteuil, Philippe Pastoureau, None, Effect of inhibition of matrix metalloproteinases on cartilage loss in vitro and in a guinea pig model of osteoarthritis Arthritis & Rheumatism. ,vol. 52, pp. 171- 180 ,(2005) , 10.1002/ART.20900
Mohit Kapoor, Johanne Martel-Pelletier, Daniel Lajeunesse, Jean-Pierre Pelletier, Hassan Fahmi, Role of proinflammatory cytokines in the pathophysiology of osteoarthritis Nature Reviews Rheumatology. ,vol. 7, pp. 33- 42 ,(2011) , 10.1038/NRRHEUM.2010.196
Jeremy Saklatvala, Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis. Current Drug Targets. ,vol. 8, pp. 305- 313 ,(2007) , 10.2174/138945007779940115
Masahiko Kobayashi, Ginette R. Squires, Aisha Mousa, Michael Tanzer, David J. Zukor, John Antoniou, Ulrich Feige, A. Robin Poole, Role of interleukin-1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage Arthritis & Rheumatism. ,vol. 52, pp. 128- 135 ,(2005) , 10.1002/ART.20776
Johannes Stöve, Klaus Huch, Klaus-Peter Günther, Hanns-Peter Scharf, Interleukin-1beta induces different gene expression of stromelysin, aggrecan and tumor-necrosis-factor-stimulated gene 6 in human osteoarthritic chondrocytes in vitro. Pathobiology. ,vol. 68, pp. 144- 149 ,(2000) , 10.1159/000055915